Featured Research

New vitamin D research is always coming out, but not all of it gets the media’s attention or is easy to find. For your convenience, we’ve put together lists of some of the research we find most noteworthy below, along with links so you can read more about them.

Reviews of Vitamin D

Michael Holick (with a Ph.D. in Biochemistry as well as an M.D.) has been pushing research on vitamin D forward for decades. If you have access to The New England Journal of Medicine, you can read his 2007 review of vitamin D here:
Vitamin D Deficiency

If not, Holick published a review of vitamin D in 2004 in The American Journal of Clinical Nutrition. You can check it our for free here:
Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease

Guidelines for Vitamin D Levels

You can view the IOM’s 2011 review of vitamin D and calcium research, along with their recommendation for consumption levels and the vitamin D blood serum levels these recommendations are based upon, here:

For actual guidelines on vitamin D blood serum levels and treatments, check out the Endocrine Society’s Clinical Guidelines:
Evolution, Treatment, and Prevent of Vitamin D Deficiency: An Endocrine Society Clinical Practice Guideline.

Regarding Vitamin D2 vs Vitamin D3

For a review of the history and differences of vitamin D2 and vitamin D3, from the different metabolic pathways they take to the problems their presumed interchangeability cause in clinical research, see this article in The American Journal of Clinical Nutrition:
The case against ergocalciferol (vitamin D2) as a vitamin supplement

If you want a more detailed look at the relative effectiveness of the two types of vitamin D (both on raising vitamin D blood serum levels and on the body’s ability to store vitamin D for a rainy day!), check out this research published in The Journal of Clinical Endocrinology and Metabolism:
Vitamin D3 is More Potent Than Vitamin D2 in Humans

Vitamin D by Speciality

Obstetrics & Gynecology, Internal Medicine, and Endocrinology

The title of this rather straightforward study in The American Journal of Obstetrics and Gynecology speaks for itself:
Pregnancy complicated by chronic hypertension: a state of vitamin D deficiency and immune activation


This article published by The American College of Cardiology contains an overview of research as it is on the effects of vitamin D upon cardiovascular health.
Vitamin D and Cardiovascular Disease


Check out this news piece from the American Journal of Orthopedics:
Vitamin D Deficiency High Among Trauma Patients


This article in The International Archives of Medicine shows correlation between vitamin D levels and depression, and includes a good discussion on the issue:
Serum vitamin D concentrations are related to depression in young adult US population: the Third National Health and Nutrition Examination Survey

A review in The British Journal of Psychiatry discusses the latest research correlating vitamin D deficiency with depression and the need for further research on the effects of vitamin D supplementation on depression:
Vitamin D deficiency and depression in adults: systematic review and meta-analysis

For a lighter read, you can check out this article at Psychology Today:
Vitamin D Deficiency and Depression